Pharma Medical USA
Pharma Medical USA Is a research-based bio pharmaceutical company that discovers, and develops OTC (over the counter) innovative, affordable, and safe medication and medicated creams. We strive to transform and simplify care for older people around the world.
Our mission is to help geriatricians to provide their patients with affordable and safer over the counter topical medications and medicated creams.
The number of over-the-counter (OTC) medications is increasing as more prescription medications are being switched to OTC status.
Many older adults rely on self-management of medications to treat common medical conditions such as the common cold, pain, diarrhea, and constipation.
When most people think of pain relief, they picture swallowing a pill. However, there also are many topical pain relievers, pain-relieving medications applied to the skin, including creams and gels.
Topical pain relievers are often used by patients who cannot take oral medications, says Biral Patel, MD, an anesthesiologist and pain management specialist at Scott & White Hospital in Temple, Texas.
“Certain patients have difficulty swallowing pills,” Dr. Patel says. “Other patients may have had surgeries that impede their ability to absorb drugs through their GI system. That’s when topical medications can be used to control pain.”
A pain relief cream can also be used when you have pain in a very specific area. “If you have pain in a joint, you can put the medication on the joint, whereas if you take the drug orally, it goes through your whole body,” Patel says.
Choices in Topical Therapy for Pain Relief:
Consider these three main types of pain medication applied to the skin
- Local anesthetics. These are medications that numb painful areas for short periods of time. They have a variety of uses. Lidocaine patches, for example, can help to relieve the burning, stabbing, chronic ache that may occur after a shingles infection- a condition called post-herpetic neuralgia. Dentists may also use a topical anesthetic on the gums to help ease the pain of an injection. Some topical local anesthetics are also available over the counter in spray and gel form to treat the sting of a sunburn.
- Pain medications. Medications applied to the skin include drugs such as the non-steroidal anti-inflammatory drug diclofenac (Solaraze, Pennsaid), which works by reducing inflammation in a localized area of the body, or aspirin creams, which work by blocking substances in the body that cause pain. Alternatively, these topical medications may contain narcotic pain relievers, such as fentanyl. Though some of these topical pain relievers (Aspercreme, BenGay) are available over the counter, some are dispensed by prescription only.
- Counter-irritants. These are products that contain substances such as menthol, eucalyptus, or oil of wintergreen that irritate nerve endings, producing a “cool” feeling on the skin and distracting the brain from deeper sources of pain. Vicks VapoRub is an example of a counter-irritant.
Why on the skin?
Here’s why: The skin is one of the best organs for administering drugs into the bloodstream, where the drug’s active ingredients are then distributed throughout the body. With oral medications, the active ingredient is metabolized (broken down) in the digestive tract, liver and kidneys, which often leads to side effects. While topical also pass through the liver and kidneys, they don’t go through the digestive tract. Advantages of topical medications…
Lower doses. When you take an oral medication, some of the active ingredient may be destroyed by acids in the digestive tract or reduced when broken down in the liver and kidneys. In fact, with some oral drugs, only about 10% of the active ingredient reaches its intended target—the bloodstream, then a specific organ or system. As a result, you must take a high dose to offset losses. Higher doses mean more complications and side effects.
Fewer side effects. Topical medications are not risk-free. But side effects are typically limited to minor skin irritation. Oral medication side effects are a major cause of hospitalization and sometimes even death.
Example: Topical medications can be helpful for patients who need narcotic painkillers. Oral narcotics often cause constipation and stomach upset. Patches are much less likely to cause these types of side effects.
Steadier dosing. When you take an oral drug, you achieve a high initial blood concentration of the active ingredient. Then, the levels slowly decline until you take the next dose. With a patch, drug levels are more evenly sustained throughout the day—or even for days at a time.
Time-released oral medications can mimic this effect, but they’re unpredictable. Many factors—the acid in your stomach, what you’ve eaten, etc.—can affect how quickly the medication is released. There’s less variability with patches.
More convenient. It’s estimated that 55% of older adults don’t take their medications the way they’re supposed to—because of forgetfulness or limited mobility, for example. Some patches can be applied once a week. It’s easier to remember once-a-week dosing than multiple daily pills.
Downside: The main drawback of topical is the cost. They are more expensive than pills because they’re more complicated to manufacture.
Pharma Medical USA is also a leader in products that address the effects of skin allergies care for health condition such as- Dermatitis, Atopic Dermatitis (Eczema),Contact Dermatitis, and anti-aging.